Top 5 Weirdest unfamiliar Psychological syndromes in the World

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Many people underestimate the seriousness of psychological issues. Every year more than a billion people all around the world are experiencing a psychological disorder. According to research conducted in the United States in 2019, roughly 29% of individuals aged 18 to 25 and 25% of those aged 26 to 49 suffered mental illness in the previous year.

The majority of these conditions are common and curable. Even the most seasoned medical or mental health specialists, on the other hand, are not completely prepared for the growing number of unusual psychological disorders.

Anxiety, stress, borderline personality disorder, schizophrenia, autism, and bipolar disorder are examples of well-known mental disorders. On the other hand, some mental disorders are so uncommon that mental health practitioners may never meet them. Here are 5 of the most unusual psychological disorders.

Top 5 Weirdest unfamiliar Psychological syndromes in the World:

Alien Hand Syndrome:

Alien hand syndrome is an uncommon neurological disorder in which one hand acts independently of the other. One leg may be affected in certain cases, but this is rare. The hand isn’t under the command of the brain in alien hand syndrome, and it moves as if it has its own mind. During these moments, the suffering hand feels strange to its owner and appears to move cleverly to do accidental actions.

Alien Hand Syndrome
Dr. Strangelove syndrome
Strangelovian hand 
anarchic hand
Alien Hand Syndrome: One’s hand acts independently of the other

Also Known As:

Dr. Strangelove syndrome, Strangelovian hand, or anarchic hand are all terms used to describe this condition.


Multiple factors can lead to alien hand syndrome,

  • Aliens hand syndrome can occur after a stroke, trauma, or cancer.
  • Aneurysms in the brain, neurological conditions, and cancer have all been related to this syndrome.
  • Alien’s Hand Syndrome is linked to brain surgeries that divide the two hemispheres of the brain. Possible surgical procedures involve cutting along the corpus callosum. The brain hemispheres are divided and can communicate with one another thanks to the corpus callosum.
  • The alien hand syndrome is a rare but serious side effect of epilepsy surgery.


  • The most evident sign of alien hand syndrome is the inability to control the hand as it performs on its own. 
  • The affected hand may move uncontrollably and perform actions and tasks with specific intent. It seems to be under the command of another person or to be acting independently.
  • Occasionally or obsessively, the hand may touch your face, button or unbutton your shirt, or pick up the products. 
  • The hand may also do self-contradictory behaviors, such as locking a drawer that the other hand had just unlocked.
  • The alien hand is uncooperative and could choose the wrong action or ignore instructions.
  • People who suffer from alien hand syndrome could feel as though their hand or another limb doesn’t relate to them.


Actually, there is no known treatment for alien hand syndrome. Scientists are working on ways to alleviate the symptoms of alien hand syndrome, but therapies and pharmaceutical possibilities are still in the early stages of research. A temporary cure may be achieved with some treatments or therapies, such as:

  • Those who suffer from alien hand syndrome following a stroke or another neurological condition may recover fully. However, treatment is less effective for those with neurological disorders.
  • To treat or manage the syndrome, neuromuscular blocking medications and muscle control therapies such as botulinum toxin (Botox) may be utilized.
  • Symptoms can be managed with the help of learning task behavioral treatments, cognitive therapy approaches, and mirror box therapy.
  • Sometimes the person will attempt to restrict their alien hand by keeping it beneath their legs, sitting on it, or putting an object in the alien hand to stop it from performing activities.

Walking Corpse Syndrome

Patients with “walking corpse syndrome,” a rare neuropsychiatric disorder, may experience feelings of impending death or loss of body parts. This syndrome covers a broad range of false beliefs, such as the conviction that one has lost one’s soul or is dead, as well as the perception that one has lost organs, blood, or other physical components.

Walking Corpse Syndrome
Cotard's delusion 
Cotard's syndrome
Walking Corpse Syndrome: Feelings of impending death or loss of body parts

Also known as:

Walking corpse syndrome is also known as  Cotard’s delusion or Cotard’s syndrome.


There is no recognized explanation for walking corpse syndrome. It can be a sign of various medical problems that impact the brain, such as: 

  • It is particularly common in persons suffering from severe depression.
  • Brain damage from a stroke, blood clot, accident, or tumor can also trigger this syndrome.
  • Drug misuse, sadness, anxiety, and mental illnesses such as schizophrenia can all contribute to this condition.
  • Other causes of walking corpse syndrome include dementia, epilepsy, Parkinson’s disease, bleeding outside the brain from severe brain injury, and multiple sclerosis.


Cotard’s syndrome, or walking corpse syndrome, is characterized by the symptoms listed below:

  • Patients with this syndrome experience illusions that they are about to die, dead, or not present.
  • The patient undergoes severe depression or sadness.
  • Patients immediately stop communicating and eventually quit participating in social activities.
  • They quit eating because they believe they are dead or dying, thus it is unnecessary, resulting in nutritional deficiencies.
  • Patients start listening to voices in their heads that say the patient is dead or close to death.
  • Other signs of walking corpse syndrome include self-harming intentions, ideas of rejection or curses, and faith in eternal life.


The main course of treatment is to identify the fundamental medical issue that causes walking corpse syndrome. Patients often receive both treatment and medication.

  • Treatments for walking corpse syndrome include: antidepressants, antipsychotics, and, anxiety-reducing drugs
  • Psychotherapy and cognitive-behavioral therapy (CBT) are both successful therapies.
  • If medicine and conversation therapy is ineffective, electroconvulsive treatment (ECT) may be employed.

Clinical Lycanthropy Syndrome

A psychiatric condition known as clinical lycanthropy causes patients to believe they have the ability to turn into wolves. It is a psychological condition in which the person experiencing this syndrome believes they can change into animals. A paranormal condition in which sufferers allegedly change into wolves physically.

Mental hallucinations associated with wolf transformation include sensory, visual, and auditory hallucinations.

Clinical lycanthropy
Clinical Lycanthropy Syndrome: Ability to turn into wolves

Also Known as:

Clinical lycanthropy is also known as zoanthropy.


  • A physical imbalance in the brain is the root of clinical lycanthropy.
  • This condition can be driven by abnormalities in certain brain regions, particularly in the cerebral cortex, which controls how an individual perceives their own body.
  • Mental illnesses including bipolar disorder, anxiety, stress, and melancholy can also cause it.


  • Lycanthropy is a shape-shifting experience; it is not unique to a transformation from a human to a wolf.
  • The person who has this syndrome says they have suffered physical and psychological transformation into an animal.
  • A person with this condition experiences hallucinations of their eyes changing color, teeth becoming longer, and hair growth when they gaze in the mirror.
  • The patient feels that a familiar place, person, thing, or aspect of their body has been imitated.
  • The patient feels a strong attraction toward forests or other types of woods.


  • Antipsychotic medicine is frequently an effective therapy for clinical lycanthropy, which is closely linked to psychotic diseases.
  • If it is a sign of depression or bipolar illness, it may also be treated with antidepressants or mood stabilizers.
  • Due to the widespread belief that the syndrome is culture-bound, patients with clinical lycanthropy may potentially benefit from a culturally sensitive approach to therapy.

Ekbom syndrome

The belief that one’s body is infected by unseen bugs is known as the Ekbom Syndrome. People with this syndrome commonly claim to experience tactile sensations and see the bugs in their minds’ eyes despite the fact that no one else can see them. Ekbom Syndrome is a delusional disorder that cannot be cured or treated by logic or facts.

Ekbom syndrome 
delusional parasitosis 
psychogenic parasitosis
Ekbom syndrome: The body is infected by unseen bugs

Also known as:

Ekbom syndrome is also known as delusional parasitosis or psychogenic parasitosis.


  • It is unclear what causes this syndrome, however, it may be caused by hallucinations or a false interpretation of itch-related sensations.
  • Prescription drugs—especially methamphetamines—are the main culprit behind the issue.
  • Stress, dry skin, psychiatric illnesses, dementia, substance misuse, and detoxification from drugs and alcohol.


  • The Ekborn patient may use tools like knives, scissors, tweezers, or fingernails to pierce their skin in an effort to discover and eliminate their unseen tormentors since the infestation feels so real to them.
  • Sufferers spend a lot of time scraping and scratching at the skin in an effort to get rid of the bugs.
  • Patients with Ekbom Syndrome spray insecticides inside their houses and automobiles as well as on their bodies using a range of pesticides, including some that are not meant for indoor use.
  • Some patients spend the majority of their waking hours cleaning the house with harsh chemicals, damaging the furniture in the process.


Ekbom syndrome must be treated with psychotherapy, but the hardest part is convincing the patient there are no parasites present and gaining their consent to see a psychiatrist. Medication or therapy provided by a psychiatrist includes:

  • Electroconvulsive treatment, conventional antipsychotics, atypical antipsychotics, antidepressants, and dermatological drugs may be treated separately or in combination.
  • Patients with Ekbom syndrome may benefit from using trifluoperazine as a therapy.

Alice in Wonderland Syndrome

Alice in Wonderland syndrome is a rare syndrome characterized by brief bouts of hallucination and confusion. It results in modifications to temporal perception, body image, and visual perception. You could perceive yourself as being bigger or smaller than you really are.

Alice in Wonderland syndrome 
Todd's syndrome
Alice in Wonderland syndrome: Bouts of hallucination and confusion

Also Known As:

The Alice in Wonderland syndrome is also known as Todd’s syndrome.


Experts in the field struggle to pinpoint the source of AWS because it only lasts a short duration.

The leading causes of AWS include the following:

  • Head trauma
  • Migraines
  • Infection
  • Brain tumors
  • Acute Disseminated Encephalomyelitis


Alice in Wonderland syndrome is a group of symptoms defined by a change in body image. Some of the symptoms include:

  • The most prevalent symptom or early warning indication of AWS is migraines. Researchers assume AWS might be a rare migraine subtype.
  • AWS patients exhibit symptoms that are either macropsia- or micropsia-related. Micropsia and macropsia are terms used to describe the sensation of your body or nearby things appearing to be getting smaller or larger, respectively.
  • One of the most frequent symptoms experienced by AWS patients is perceptual distortion, temporal distortion, and acoustic distortion.
  • This condition occurs when muscles appear to be functioning uncontrollably. The patient may notice a loss of coordination or difficulty moving around as they normally do.


The AWS condition has no known cure. However, by implementing the following specific strategies, AWS syndrome may be healed.

  • When dealing with a patient, it is better to stand back and watch them go on. Additionally, it’s essential to convince the patient that the symptoms are not life-threatening.
  • By addressing the underlying issue that the patient and patient’s doctor consider to be the cause of the issue, AWS episodes may be prevented.
  • In the same way, if an infection is treated, the symptoms may go away.
  • If the patient and the patient’s doctor believe stress is a contributing cause, meditation and relaxation tactics may help in the treatment.


According to a Chinese poll; done in December 2020, just one out of every five respondents asked claimed they did not have a prevalent psychological ailment. Psychological issues can interfere with everyday activities, relationships, employment, education, and other crucial spheres of life. People can get rid of their symptoms and learn how to manage them with the correct diagnosis and therapy.

Recognize that seeking psychological/psychiatric treatment is in no way humiliating and that it may significantly improve the quality of life for those who suffer from the most prevalent mental diseases. While the majority of people may count themselves lucky to have avoided such serious diseases.

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